Infectious Diseases

Infectious Diseases

Infectious Disease Research

About

Important viral (equine arteritis, equine influenza, equine infectious anemia, equine herpes including the abortion, paralytic and respiratory forms) and bacterial (such as the causative agent of strangles) microorganisms are being investigated by the Infectious Diseases group. In addition to laboratory-based studies, the incidence of infectious diseases in horses throughout the country is closely monitored, and studies are conducted to assist horse owners and veterinarians in managing severe outbreaks including those caused by bioterrorism.

Areas of Research


Research Output

A fully human monoclonal antibody possesses antibody-dependent cellular cytotoxicity (ADCC) activity against the H1 subtype of influenza A virus by targeting a conserved epitope at the HA1 protomer interface

Rongyuan Gao, Zhao Wang, Tirth Uprety, Chithra C. Sreenivasan, Zizhang Sheng, Ben M. Hause, Colin Brunick, Hua Wu, Thomas Luke, Christoph L. Bausch, Eddie J. Sullivan, Adam D. Hoppe, Victor C. Huber, Dan Wang, Feng Li

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A recombinant chimeric influenza virus vaccine expressing the consensus H3 hemagglutinin elicits broad hemagglutination inhibition antibodies against divergent swine H3N2 influenza viruses

Jieshi Yu, Chithra Sreenivasan, Zhizhang Sheng, Shao Lun Zhai, Jared W. Wollman, Sisi Luo, Chen Huang, Rongyuan Gao, Zhao Wang, Radhey S. Kaushik, Jane Christopher-Hennings, Eric Nelson, Ben M. Hause, Feng Li, Dan Wang

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Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond—A Comprehensive Review

Ajran Kabir, Bibek Lamichhane, Tasmia Habib, Alexis Adams, Hossam El-Sheikh Ali, Nathan M. Slovis, Mats H.T. Troedsson, Yosra A. Helmy

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Contact Information

Brett Sponseller
Director, Gluck Equine Research Center

108A Gluck Equine Research Center 1400 Nicholasville Rd. Lexington, KY 40546-0215

(859) 257-4757

brett.sponseller@uky.edu